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Vaisheshika or Vaiśeṣika is one of the six orthodox schools of Hinduism from ancient India. In its early stages, the Vaiśeṣika was an independent philosophy with its own metaphysics, epistemology, logic, ethics, and soteriology. Over time, the Vaiśeṣika system became similar in its philosophical procedures, ethical conclusions and soteriology to the Nyāya school of Hinduism, but retained its difference in epistemology and metaphysics.

Vaisheshika or Vaiśeṣika (Sanskrit: वैशेषिक) is one of the six orthodox schools of Hinduism (Vedic systems) from ancient India. In its early stages, the Vaiśeṣika was an independent philosophy with its own metaphysics, epistemology, logic, ethics, and soteriology. Over time, the Vaiśeṣika system became similar in its philosophical procedures, ethical conclusions and soteriology to the Nyāya school of Hinduism, but retained its difference in epistemology and metaphysics.

The epistemology of Vaiśeṣika school of Hinduism, like Buddhism, accepted only two reliable means to knowledge: perception and inference. Vaiśeṣika school and Buddhism both consider their respective scriptures as indisputable and valid means to knowledge, the difference being that the scriptures held to be a valid and reliable source by Vaiśeṣikas were the Vedas.

Vaisheshika school is known for its insights in naturalism, and it is a form of atomism in natural philosophy. It postulated that all objects in the physical universe are reducible to paramāṇu (atoms), and one's experiences are derived from the interplay of substance (a function of atoms, their number and their spatial arrangements), quality, activity, commonness, particularity and inherence. According to Vaiśeṣika school, knowledge and liberation were achievable by complete understanding of the world of experience.

Vaiśeṣika darshana was founded by Kaṇāda Kashyapa around the 2nd century BC.