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A late-night talk show is a genre of talk show popular in the US, structured around humorous monologues about the day's news, guest interviews, comedy sketches and music performances. The late-night talk show format was popularized, though not invented, by Johnny Carson with The Tonight Show Starring Johnny Carson on NBC. Typically the show's host conducts interviews from behind a desk, while the guest is seated on a couch. Many late night talk shows feature a house band which generally performs cover songs for the studio audience during commercial breaks and occasionally will back up a guest artist.

Late-night talk shows often feature guest interviews. Here, Barack Obama is interviewed by David Letterman.

A late-night talk show is a genre of talk show popular in the US, structured around humorous monologues about the day's news, guest interviews, comedy sketches and music performances. The late-night talk show format was popularized, though not invented, by Johnny Carson with The Tonight Show Starring Johnny Carson on NBC. Typically the show's host conducts interviews from behind a desk, while the guest is seated on a couch. Many late night talk shows feature a house band which generally performs cover songs for the studio audience during commercial breaks and occasionally will back up a guest artist.

Late-night talk shows are a popular format in the United States, but are not as prominent in other parts of the world. Shows that loosely resemble the format air in other countries, but generally air weekly as opposed to the nightly airings of those in the United States. They also generally air in time slots considered to be prime time in the United States.